Scientific Studies

Journal of Exercise and Nutrition 2021 

A placebo-controlled crossover design study involving nine healthy men between the ages of 18 and 45 years was conducted to investigate the effects of caffeine, methylliberine (Dynamine™), and theacrine (TeaCrine®) on cognitive and motor performance during a first-person shooter video game.

KEY FINDING:

  • Supports working memory, cognitive control, and reaction time during mentally and physically demanding tasks.*

Source: Effects of TeaCrine® (theacrine), Dynamine™ (methylliberine), and caffeine on gamer psychomotor performance in a first-person shooter video game scenario

Journal: Cureus 2021

A placebo-controlled, repeated-measure, randomized crossover study involving 50 young male participants was conducted to investigate the effects of caffeine, Dynamine®, and TeaCrine® on e-gamer performance.

KEY FINDING:

  • Supports improved cognitive performance without increasing self-reported anxiety or headaches.*

Source: A Combination of Caffeine, TeaCrine® (Theacrine), and Dynamine® (Methylliberine) Increases Cognitive Performance and Reaction Time Without Interfering With Mood in Adult Male E-gamers

Journal: Medicine 2023

A randomized, double-blind, placebo-controlled study involving 66 participants was conducted over 4 weeks to determine the effect of Bacillus coagulans MTCC 5856 (LactoSpore®) on functional gas and bloating in healthy adults.

KEY FINDING:

  • Supports reductions in abdominal gas and distension.

Source: The effects of Bacillus coagulans MTCC 5856 on functional gas and bloating in adults: A randomized, double-blind, placebo-controlled study

Journal: Medicine 2023

A randomized, double-blind, placebo-control study involving 30 participants was conducted over 28 days to determine the effect of Bacillus coagulans MTCC 5856 (LactoSpore®) on microbiota composition.

KEY FINDING:

  • Supports an increase in beneficial gut bacteria.

Source: Probiotic modulation of gut microbiota by Bacillus coagulans MTCC 5856 in healthy subjects: A randomized, double-blind, placebo-control study

American Journal of Physiology – Endocrine and Metabolism 2015 

A randomized controlled trial involving 16 participants was conducted to study the effects of leucine-enriched amino acids and whey protein at rest and after resistance exercise in older women.

KEY FINDING:

  • Helps to stimulate muscle protein anabolism.* 

Source: Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise

Clinical Nutrition 2018

A randomized controlled trial involving 24 participants was conducted to evaluate the effects of leucine-enriched amino acids on muscle protein synthesis compared to a large bolus of whey protein in older women.

KEY FINDING:

  • Supports muscle protein balance by increasing anabolism and limiting catabolism.* 

Source: Probiotic modulation of gut microbiota by Bacillus coagulans MTCC 5856 in healthy subjects: A randomized, double-blind, placebo-control study

American Journal of Physiology – Endocrine and Metabolism 2006 

A clinical trial involving 36 participants was conducted to evaluate the effects of enriching an essential amino acid (EAA) mixture with leucine on muscle protein metabolism in elderly and young individuals.

KEY FINDING:

  • Supports stimulation of muscle protein synthesis.* 

Source: A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly

Journal: Biological and Pharmaceutical Bulletin 2016

A clinical trial involving 4 healthy male participants was conducted to evaluate the absorption and urinary excretion of peptides after collagen tripeptide (Collameta™) ingestion. 

KEY FINDING:

  • Supports improved efficiency of peptide absorption.* 

Source: Absorption and Urinary Excretion of Peptides after Collagen Tripeptide Ingestion in Humans

Journal: Phytotherapy Research 2014 

A randomized, double-blind, placebo-controlled trial involving 40 participants was conducted to evaluate the efficacy of a bioavailability-boosted curcuminoids (C3 complex®) in the alleviation of knee osteoarthritis symptoms.

KEY FINDING:

  • Helps to relieve pain associated with osteoarthritis.* 

Source: Curcuminoid Treatment for Knee Osteoarthritis: A Randomized Double-Blind Placebo-Controlled Trial (link

Journal: Nutrition 2016 

A randomized, double-blind, placebo-controlled trial involving 117 participants was conducted over 8 weeks to investigate the effect of curcumin (C3 complex®) on circulating adiponectin and leptin concentrations in patients with metabolic syndrome.

KEY FINDING:

  • Supports improvement of adipokines levels, hormones that regulate fat metabolism.* 

Source: Effects of supplementation with curcumin on serum adipokine concentrations: A randomized controlled trial

Journal of the International Society of Sports Nutrition 2017 

A randomized, double-blind, single-dose, comparator-controlled crossover trial involving 10 participants was conducted to investigate the effects of an amylopectin/chromium complex (Velositol®) on plasma concentrations of essential amino acids (EAA), insulin, glucose, and the fractional rate of muscle protein synthesis (FSR).

KEY FINDING:

  • Supports an increase in muscle protein synthesis.* 

Source: Effects of amylopectin and chromium complex on the anabolic response to a suboptimal dose of whey protein.

Journal of Exercise and Nutrition 2021  

A randomized, active-controlled, double-blind study involving 35 recreationally active men was conducted to investigate the effects of an amylopectin-chromium complex (Velositol®) combined with whey protein on strength and power after 8 weeks of resistance training.

KEY FINDINGS:

  • Supports an increase in muscular endurance and power.*
  • May decrease diastolic blood pressure.*

Journal of Exercise and Nutrition 2021  

V15P = 2 g amylopectin-chromium complex+ 15 g whey protein isolate 

15P = 15 g of whey protein isolate 

30P = 30 g of whey protein isolate

Journal of Exercise and Nutrition 2021  

Source: Effects of an Amylopectin-Chromium Complex Plus Whey Protein on Strength and Power After Eight Weeks of Resistance Training