A clinical trial involving 4 healthy male participants was conducted to evaluate the absorption and urinary excretion of peptides after collagen tripeptide (Collameta™) ingestion. 

KEY FINDING:

• Supports improved efficiency of peptide absorption.* 

Source: Absorption and Urinary Excretion of Peptides after Collagen Tripeptide Ingestion in Humans (link) 

A randomized, double-blind, placebo-controlled trial involving 40 participants was conducted to evaluate the efficacy of a bioavailability-boosted curcuminoids (C3 complex®) in the alleviation of knee osteoarthritis symptoms.

KEY FINDING:

• Helps to relieve pain associated with osteoarthritis.* 

Source: Curcuminoid Treatment for Knee Osteoarthritis: A Randomized Double-Blind Placebo-Controlled Trial (link) 

A randomized, double-blind, placebo-controlled trial involving 117 participants was conducted over 8 weeks to investigate the effect of curcumin (C3 complex®) on circulating adiponectin and leptin concentrations in patients with metabolic syndrome.

KEY FINDING:

• Supports improvement of adipokines levels, hormones that regulate fat metabolism.* 

Source: Effects of supplementation with curcumin on serum adipokine concentrations: A randomized controlled trial (link) 

A randomized, double blind, crossover, placebo-controlled trial involving 37 participants aged 18 to 65 was conducted over 60 days to investigate the effects of curcumin (C3 complex®) on serum cytokines in obese individuals.

KEY FINDING:

• May exert immunomodulatory effects via alteration of serum cytokine levels.* 

Source: Investigation of the Effects of Curcumin on Serum Cytokines in Obese Individuals: A Randomized Controlled Trial (link) 

A randomized, placebo-controlled trial involving 100 patients with metabolic syndrome was conducted over 8 weeks to evaluate the lipid-modifying effects of bioavailability-enhanced curcuminoids (C3 complex®).

KEY FINDING:

• Supports areduction in LDL cholesterol (“bad cholesterol”).*
• Supports anincrease in HDL cholesterol (“good cholesterol”).* 

Source: Lipid-modifying effects of adjunctive therapy with curcuminoids–piperine combination in patients with metabolic syndrome: Results of a randomized controlled trial (link)